April 20th, 2021 - 2021—Read the original CpG-depletion AAV vector technology scientific article, Faust et al., JCI, 2013. We were the first to develop and demonstrate that CpG-depleted AAV vectors could establish persistent transgene expression, evade immunity, and minimize infiltration of effector cells. We concluded and accurately predicted that CpG-depleted AAV vectors could improve outcome of clinical trials of gene therapy.