The title of the abstract is CpG-Motifs within AAV Vectors Trigger Immune Activation upon Hepatic Gene Transfer. The results demonstrate that CpG depletion of AAV vector genomes provide an avenue to improve the clinical outcome of AAV-mediated gene transfer by preventing elimination of transgene product expressing hepatocytes by vector-induced T cell responses.
February 14th, 2020 - February 14, 2020 – NxGEN Vector Solutions has submitted a scientific abstract to the 23rd Annual Meeting of American Society of Gene and Cellular Therapy, Boston, Massachusetts, May 12-15, 2020.
